CNTNAP4
Function
Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory interneuron synapses. Involved in the dopaminergic synaptic transmission by attenuating dopamine release through a presynaptic mechanism. Also participates in the GABAergic system (By similarity).
Sequence Similarities
Belongs to the neurexin family.
Cellular localization
- Presynaptic cell membrane
- Single-pass type I membrane protein
- Specifically present within the presynaptic compartment of synapses.
Alternative names
CASPR4, KIAA1763, CNTNAP4, Contactin-associated protein-like 4, Cell recognition molecule Caspr4