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COMMD7

Function

May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Associates with the NF-kappa-B complex and suppresses its transcriptional activity (PubMed:15799966).

Tissue Specificity

Widely expressed with highest expression in lung.

Cellular localization

Alternative names

C20orf92, COMMD7, COMM domain-containing protein 7

swissprot:Q86VX2 entrezGene:149951