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Function

Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.

Sequence similarities

Belongs to the peptidase M14 family.

Tissue specificity

Plasma; synthesized in the liver.

Cellular localization

  • Secreted

Alternative names

Tafi, Cpb2, Carboxypeptidase B2, Carboxypeptidase R, Carboxypeptidase U, Thrombin-activable fibrinolysis inhibitor, CPR, CPU, TAFI

Target type

Proteins

Molecular weight

48871Da

We found 1 product in 1 category

Proteins & Peptides

Species of origin

Search our catalogue for 'CPB2' (1)

Products