CPB2

Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.

N-glycosylated. N-glycan at Asn-108: Hex5HexNAc4.

Belongs to the peptidase M14 family.

Plasma; synthesized in the liver.

• Secreted

Carboxypeptidase B2, Carboxypeptidase U, Plasma carboxypeptidase B, Thrombin-activable fibrinolysis inhibitor, CPU, pCPB, TAFI, CPB2

• entrezGene:1361
• omim:603101
• swissprot:Q96IY4

Proteins

48424Da