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CPVL

Function

May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.

Sequence Similarities

Belongs to the peptidase S10 family.

Tissue Specificity

Expressed in macrophages but not in other leukocytes. Abundantly expressed in heart and kidney. Also expressed in spleen, leukocytes, and placenta.

Alternative names

VLP, PSEC0124, UNQ197/PRO223, CPVL, Probable serine carboxypeptidase CPVL, Vitellogenic carboxypeptidase-like protein, VCP-like protein, hVLP

swissprot:Q9H3G5 omim:609780 entrezGene:54504