Creatine kinase S-type, mitochondrial
Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Sequence Similarities
Belongs to the ATP:guanido phosphotransferase family.
Tissue Specificity
Sarcomere-specific. Found only in heart and skeletal muscles.
Cellular localization
- Mitochondrion inner membrane
- Peripheral membrane protein
- Intermembrane side
Alternative names
Basic-type mitochondrial creatine kinase, Sarcomeric mitochondrial creatine kinase, Mib-CK, S-MtCK, CKMT2