CRLF3

May play a role in the negative regulation of cell cycle progression.

Belongs to the cytokine receptor-like factor 3 family.

Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer types. Also detected in lesion actinic keratosis (AK).

• Cytoplasm
• The EGFP- and MYC-tagged protein has been shown to be cytoplasmic.

CREME9, CRLM9, CYTOR4, P48, CRLF3, Cytokine receptor-like factor 3, Cytokine receptor-like molecule 9, Cytokine receptor-related protein 4, Type I cytokine receptor-like factor p48, CREME-9

• entrezGene:51379
• omim:614853
• swissprot:Q8IUI8

Proteins

49766Da