CRNKL1
Function
Involved in pre-mRNA splicing process (PubMed:11991638, PubMed:12084575, PubMed:28076346, PubMed:28502770). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).
Sequence Similarities
Belongs to the crooked-neck family.
Tissue Specificity
Widely expressed (PubMed:11342225). Highly expressed in testis (PubMed:12084575). Not detected in brain and lung (PubMed:12084575).
Cellular localization
- Nucleus
- Nucleus speckle
- Colocalizes with core spliceosomal snRNP proteins (PubMed:12084575).
Alternative names
CRN, CGI-201, MSTP021, CRNKL1, Crooked neck-like protein 1, Crooked neck homolog, hCrn