CRP

Function

Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

Sequence Similarities

Belongs to the pentraxin family.

Tissue Specificity

Found in plasma.

Cellular localization

• Secreted

Alternative names

PTX1, CRP, C-reactive protein

Database links

swissprot:P02741 entrezGene:1401 omim:123260

Other research areas

• Cardiovascular
• Neuroscience