The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Pulmonary surfactant metabolism dysfunction 4
SMDP4
A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
None
The disease is caused by variants affecting the gene represented in this entry.
Belongs to the type I cytokine receptor family. Type 5 subfamily.
Proteins
Immunology & Infectious Disease
46207Da
We found 17 products in 3 categories
ab95681
ab202851
ab238104
ab233574