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G-CSF

Function

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.

Post-translational modifications

O-glycosylated.

Sequence similarities

Belongs to the IL-6 superfamily.

Cellular localization

  • Secreted

Alternative names

  • Granulocyte colony-stimulating factor
  • G-CSF
  • Csfg
  • Csf3

Target type

Proteins

Primary research area

Immuno-oncology

Other research areas

  • Immunology & Infectious Disease

Molecular weight

22421Da