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CSF3
Function
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Post-translational modifications
O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).
Sequence similarities
Belongs to the IL-6 superfamily.
Cellular localization
- Secreted
Alternative names
- Granulocyte colony-stimulating factor
- G-CSF
- Pluripoietin
- GCSF
- C17orf33
- CSF3
Database links
Target type
Proteins
Primary research area
Immuno-oncology
Other research areas
- Immunology & Infectious Disease
Molecular weight
22293Da