CSH2

Function

Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.

Sequence Similarities

Belongs to the somatotropin/prolactin family.

Cellular localization

• Secreted

Alternative names

Chorionic somatomammotropin hormone 2, Choriomammotropin, Lactogen, Placental lactogen, PL, CSH2

Database links

swissprot:P0DML3 entrezGene:1443 entrezGene:1442 omim:118820 swissprot:P01243