Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (PubMed:11239457, PubMed:16818610). Participates in Wnt signaling (By similarity).
Poirier-Bienvenu neurodevelopmental syndrome
POBINDS
An autosomal dominant neurodevelopmental disorder characterized by onset of seizures in infancy, developmental delay, impaired intellectual development, and poor or absent speech.
None
The disease is caused by variants affecting the gene represented in this entry.
Phosphorylated by alpha subunit.
Belongs to the casein kinase 2 subunit beta family.
Proteins
24942Da
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