CSRP2
Function
Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
Tissue Specificity
Highly expressed in the aorta, but not in heart and skeletal muscle.
Cellular localization
- Nucleus
Alternative names
LMO5, SMLIM, CSRP2, Cysteine and glycine-rich protein 2, Cysteine-rich protein 2, LIM domain only protein 5, Smooth muscle cell LIM protein, CRP2, LMO-5, SmLIM