CST11
Function
Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization.
Sequence Similarities
Belongs to the cystatin family.
Tissue Specificity
Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level).
Cellular localization
- Secreted
- Probably secreted into the epididymis lumen, where it localizes to the outer surface of sperm. Specifically localizes to the postacrosomal and tail regions of sperm.
Alternative names
CST8L, CST11, Cystatin-11