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Function

Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).

Isoform 2 probably acts as a scaffold for specialized synapses.

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

Tissue specificity

Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas.

Cellular localization

  • Nucleus
  • Synapse

Alternative names

C-terminal-binding protein 2, CtBP2, CTBP2

Target type

Proteins

Primary research area

Neuroscience

Molecular weight

48945Da