Ctf1
Function
Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
Sequence Similarities
Belongs to the IL-6 superfamily.
Tissue Specificity
Highly expressed in heart, skeletal muscle, liver, lung and kidney. Lower levels in testis and brain. No expression in spleen.
Cellular localization
- Secreted
Alternative names
Cardiotrophin-1, CT-1, Ctf1