CTF1
Function
Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
Sequence Similarities
Belongs to the IL-6 superfamily.
Tissue Specificity
Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes.
Cellular localization
- Secreted
Alternative names
Cardiotrophin-1, CT-1, CTF1