CTSS
Function
Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation (PubMed:30612035). The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
Sequence Similarities
Belongs to the peptidase C1 family.
Cellular localization
- Lysosome
- Secreted
- Cytoplasmic vesicle
- Phagosome
Alternative names
Cathepsin S, CTSS