Cxcl2
Function
Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. Contributes to neutrophil activation during inflammation.
Sequence Similarities
Belongs to the intercrine alpha (chemokine CxC) family.
Tissue Specificity
At least expressed in the lung and trachea.
Cellular localization
- Secreted
Alternative names
Cinc3, Mip-2, Mip2, Scyb2, Cxcl2, C-X-C motif chemokine 2, Cytokine-induced neutrophil chemoattractant 3, Macrophage inflammatory protein 2, CINC-3, MIP2