GCP2

Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).

Belongs to the intercrine alpha (chemokine CxC) family.

• Secreted

GCP2, SCYB6, CXCL6, C-X-C motif chemokine 6, Chemokine alpha 3, Granulocyte chemotactic protein 2, Small-inducible cytokine B6, CKA-3, GCP-2

• entrezGene:6374
• entrezGene:6372
• omim:600324
• omim:138965
• swissprot:P80162
• swissprot:P42830

Proteins

Immuno-oncology

11897Da