CXCR6

Function

Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.

Sequence Similarities

Belongs to the G-protein coupled receptor 1 family.

Tissue Specificity

Expressed in lymphoid tissues and activated T cells.

Cellular localization

• Cell membrane
• Multi-pass membrane protein

Alternative names

CD186, BONZO, STRL33, TYMSTR, CXCR6, C-X-C chemokine receptor type 6, CXC-R6, CXCR-6, CDw186, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo

Database links

swissprot:O00574 entrezGene:10663 omim:605163

Other research areas

• Immuno-oncology