CXXC1
Domain
The acidic domain carries the potential to activate transcription.
Function
Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.
Post-translational modifications
May be regulated by proteolysis.
Tissue Specificity
Ubiquitous.
Cellular localization
- Nucleus speckle
- Nucleus
- Associated with euchromatin. During mitosis, excluded from condensed chromosomes.
Alternative names
CFP1, CGBP, PCCX1, PHF18, CXXC1, CXXC-type zinc finger protein 1, CpG-binding protein, PHD finger and CXXC domain-containing protein 1