cysH
Domain
The open, reduced form of PAPS reductase is able to bind PAPS, whereas the closed oxidized form cannot. A movement between the two monomers of the dimer may allow this switch in conformation to occur.
Function
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
Pathway
Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3.
Sequence Similarities
Belongs to the PAPS reductase family. CysH subfamily.
Cellular localization
- Cytoplasm
Alternative names
b2762, JW2732, cysH, Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS sulfotransferase, PAdoPS reductase