DAZAP1
Function
RNA-binding protein, which may be required during spermatogenesis.
Post-translational modifications
Acetylation at Lys-150 is predominantly observed in the nuclear fraction, and may regulate nucleocytoplasmic transport.
Tissue Specificity
Mainly expressed in testis. Expressed to a lower level in thymus. Weakly or not expressed in heart, liver, brain, placenta, lung, skeletal muscle, kidney and pancreas.
Cellular localization
- Cytoplasm
- Nucleus
- Predominantly cytoplasmic (By similarity). Nuclear at some stages of spermatozoides development. In midpachytene spermatocytes, it is localized in both the cytoplasm and the nuclei and is clearly excluded from the sex vesicles. In round spermatids, it localizes mainly in the nuclei, whereas in elongated spermatids, it localizes to the cytoplasm (By similarity).
Alternative names
DAZ-associated protein 1, Deleted in azoospermia-associated protein 1, DAZAP1