DDA1
Function
Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:17452440, PubMed:28302793, PubMed:28437394, PubMed:31686031, PubMed:31819272). In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex (PubMed:31686031, PubMed:31819272).
Pathway
Protein modification; protein ubiquitination.
Sequence Similarities
Belongs to the DDA1 family.
Alternative names
C19orf58, PCIA1, DDA1, DET1- and DDB1-associated protein 1, Placenta cross-immune reaction antigen 1, PCIA-1