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DDC

Function

Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin.

Pathway

Catecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 2/2.

Sequence Similarities

Belongs to the group II decarboxylase family.

Alternative names

Aromatic-L-amino-acid decarboxylase, AADC, DOPA decarboxylase, DDC

swissprot:P27718 entrezGene:280762