DDIT4L
Function
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
Sequence Similarities
Belongs to the DDIT4 family.
Tissue Specificity
Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery.
Cellular localization
- Cytoplasm
Alternative names
REDD2, RTP801L, DDIT4L, DNA damage-inducible transcript 4-like protein, HIF-1 responsive protein RTP801-like, Protein regulated in development and DNA damage response 2, REDD-2