DDX27
Domain
The C-terminal domain regulates nucleolar localization (PubMed:25825154).
Function
Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA (PubMed:25825154).
Sequence Similarities
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
Cellular localization
- Nucleus
- Nucleolus
- Chromosome
- Associates with 60S and 90S pre-ribosomal particles (PubMed:25825154).
Alternative names
cPERP-F, RHLP, HSPC259, PP3241, DDX27, Probable ATP-dependent RNA helicase DDX27, DEAD box protein 27