DDX41
Function
Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing.
Involvement in disease
Myeloproliferative/lymphoproliferative neoplasms, familial
MPLPF
A familial cancer predisposition syndrome with incomplete penetrance, characterized by increased susceptibility to myeloid neoplasms and rarely to lymphoid malignancies. MPLPF inheritance is autosomal dominant.
None
Disease susceptibility is associated with variants affecting the gene represented in this entry.
Sequence Similarities
Belongs to the DEAD box helicase family. DDX41 subfamily.
Cellular localization
- Nucleus
Alternative names
ABS, DDX41, Probable ATP-dependent RNA helicase DDX41, DEAD box protein 41, DEAD box protein abstrakt homolog