DDX47
Function
Required for efficient ribosome biogenesis (By similarity). May have a role in mRNA splicing (PubMed:16963496). Involved in apoptosis (PubMed:15977068).
Sequence Similarities
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
Tissue Specificity
Expressed in skin, lung and breast. Also expressed in the brain.
Cellular localization
- Nucleus
- Nucleolus
- Localizes in the nucleolar-organizing region during ribosome biogenesis.
Alternative names
Probable ATP-dependent RNA helicase DDX47, DEAD box protein 47, DDX47