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def

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).

Sequence Similarities

Belongs to the polypeptide deformylase family.

Alternative names

def1, pdf1, def, Peptide deformylase, PDF, Polypeptide deformylase

swissprot:P68826