JavaScript is disabled in your browser. Please enable JavaScript to view this website.

Defactinib

Alternative names

0610042I06Rik, 1B07_HUMAN, 2610017K16Rik, 2810468K05Rik, 39 kDa protein kinase, AI327312, AIK, AIK2, ARK-1, ARK-2, AS, AU020252, AURA, AURKB_HUMAN, AURORA/IPL1-like kinase, AurB, Aurora 1, Aurora 2, Aurora A, Aurora kinase A, Aurora kinase B, Aurora- and Ipl1-like midbody-associated protein 1, Aurora-B, Aurora-related kinase 1, Aurora-related kinase 2, Aurora/IPL1-related kinase 1, Aurora/IPL1-related kinase 2, B-4901, B-7 alpha chain, BTAK, BTF2 p80, Basic transcription factor 2 80 kDa subunit, Breast tumor-amplified kinase, C-2K, C-TAK1, CADTK, CAK, CAK 1, CAK-beta, CAKB, CD 135, CD135 antigen, CD38 negative kinase 1, CDC2-related protein kinase 5, CDC2-related protein kinase 7, CDC28, CDC28A, CDC2A, CDC2L, CDC2L4, CDK-activating kinase, CDK-activating kinase 1, CDK12_HUMAN, CDK13_HUMAN, CDK1_HUMAN, CDK2_HUMAN, CDK5_HUMAN, CDK7_HUMAN, CDK9_HUMAN, CDKL5_HUMAN, CDKN1, CDKN2, CDKN7, CELL CYCLE CONTROLLER CDC2, CHED, CK II, CK II alpha', CK2A2, COFS 2, CRK7, CRKR, CSK22_HUMAN, CTCL tumor antigen HD CL 09, CTCL-associated antigen HD-CL-09, CXPD, Calcium regulated non receptor proline rich tyrosine kinase, Calcium-dependent tyrosine kinase, Casein kinase 2 alpha prime polypeptide, Casein kinase II alpha' chain, Casein kinase II subunit alpha', Cdc 2, Cdc2 related kinase arginine/serine rich, Cdc2-related kinase, Cdc25C-associated protein kinase 1, Cell Divsion Cycle 2 Protein, Cell adhesion kinase beta, Cell devision kinase 2, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, Cell division cycle 2-like protein kinase 4, Cell division cycle 2-like protein kinase 5, Cell division cycle 2-related protein kinase 7, Cell division protein kinase 1, Cell division protein kinase 12, Cell division protein kinase 13, Cell division protein kinase 2, Cell division protein kinase 5, Cell division protein kinase 7, Cell division protein kinase 9, Cholinesterase-related cell division controller, Crk6, CrkRS, Cutaneous T cell lymphoma tumor antigen HD CL 09, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, Cyclin dependent kinase 5 transcript, Cyclin-dependent kinase 1, Cyclin-dependent kinase 12, Cyclin-dependent kinase 13, Cyclin-dependent kinase 2, Cyclin-dependent kinase 5, Cyclin-dependent kinase 7, Cyclin-dependent kinase 9, Cyclin-dependent kinase-like 5, D130018F14Rik, DKFZp434J037, DKFZp666H245, DKFZp686D0638, DKFZp686F01113, DKFZp686I18166, DKFZp686L20222, DNA excision repair protein ERCC-2, DNA repair protein complementing XP-D cells, DPK, DYR1A_HUMAN, DYRK, DYRK 1, DYRKA, Dendritic cell-derived protein kinase, Dual specificity YAK 1 related kinase, Dual specificity YAK1-related kinase, Dual specificity tyrosine (Y) phosphorylation regulated kinase 1A, Dual specificity tyrosine phosphorylation regulated kinase, Dual specificity tyrosine phosphorylation regulated kinase 1, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, E430023O05Rik, EC 2.7.10.2, EC 2.7.11.1, EC 2.7.11.22, EC 2.7.11.25, EDPK, EIEE2, ELKL motif kinase, ELKL motif kinase 1, ELKL motif kinase 2, EM9, EMK-1, EMK-2, ERCC2_HUMAN, ETK 1, Excision repair 2, Excision repair cross complementing rodent repair deficiency complementation, Excision repair cross complementing rodent repair deficiency, complementation group 2, F52, FADK, FADK 1, FADK 2, FAK related non kinase polypeptide, FAK1_HUMAN, FAK2_HUMAN, FER_HUMAN, FL cytokine receptor, FLJ14314, FLJ16446, FLJ31808, FLJ39635, FLJ43934, FLJ90349, FLJ90748, FLT3_HUMAN, FRNK, Feline encephalitis virus related kinase FER, Fer (fps/fes related) tyrosine kinase, Fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94), FerT, Fetal liver kinase 2, Flk 2, Fms related tyrosine kinase 3, Fms-like tyrosine kinase 3, Focal adhesion Kinase, Focal adhesion kinase 1, Focal adhesion kinase 2, Focal adhesion kinase isoform FAK Del33, Focal adhesion kinase related nonkinase, Fujinami poultry sarcoma/Feline sarcoma related protein Fer, GSK-3 alpha, GSK-3 beta, GSK3A_HUMAN, GSK3B_HUMAN, GSK3beta isoform, Glycogen synthase kinase-3 alpha, Glycogen synthase kinase-3 beta, Growth factor receptor tyrosine kinase type III, HC class I antigen SHCHA, HCAK, HLA class I histocompatibility antigen, HLA class I histocompatibility antigen, B alpha chain, HLA-B histocompatibility type, HP 86, HPK 38, HPK1, Hematopoietic progenitor kinase, Hematopoietic progenitor kinase 1, High affinity nerve growth factor receptor, High affinity nerve growth factor receptor precursor, Homolog of Xenopus MO15 Cdk activating kinase, Human Hematopoietic Progenitor Kinase, IAK, IPL1, IPL1 related kinase, ISSX, JIK, JNK/SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, KB 1458E12.1, KDS, KIAA0175, KIAA1142, KIAA1361, KIAA4230, KP78, KRCT, KRS1, Kinase from chicken homolog A, Kinase from chicken homolog B, Kinase of embryonic stem cells, Kinase responsive to stress, Kinase responsive to stress 1, Kinase subunit of CAK, Kos 1, Krs2, LATS large tumor suppressor homolog 1, LATS1_HUMAN, Large tumor suppressor homolog 1, Likely ortholog of maternal embryonic leucine zipper kinase, Ly-72, M3K11_HUMAN, M4K1_HUMAN, MAP microtubule affinity regulating kinase 3, MAP/microtubule affinity-regulating kinase 2, MAP/microtubule affinity-regulating kinase 3, MAP3K16, MAP3K18, MAPK/ERK kinase kinase kinase 1, MARK kinase, MARK2_HUMAN, MARK3_HUMAN, MARKK, MEK kinase kinase 1, MEKK11, MEKKK 1, MELK_HUMAN, MGC102762, MGC105683, MGC111195, MGC124628, MGC126218, MGC126219, MGC16211, MGC17114, MGC29021, MGC34538, MGC46193, MGC99619, MHC Class I HLA heavy chain, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC class 1 antigen, MHC class I antigen HLA-B alpha chain, MHC class I antigen HLA-B heavy chain, MHC class I molecule, MHC class I-antigen B*7, MNB, MNB protein kinase, MNB protein kinase, Serine/threonine-specific, MNB/DYRK protein kinase, MNBH, MO15, MO15, Xenopus, homolog of, MPF, MPK38, MPSK, MPSK1, MRD7, MST-1, MST-2, MST-3, MTC, Mammalian STE20-like protein kinase 1, Mammalian STE20-like protein kinase 2, Mammalian sterile 20 like 1, Mammalian sterile 20-like 2, Map3k11, Map4k1, Maternal embryonic leucine zipper kinase, Mess1, Microtubule affinity regulating kinase kinase, Minibrain (Drosophila) homolog, Minibrain homolog, Minibrain, Drosophila, homolog of, Mitogen-activated protein kinase kinase kinase 11, Mitogen-activated protein kinase kinase kinase kinase 1, Mixed lineage kinase 3, Mixed lineage protein kinase 3, Mnb protein kinase homolog hp86, Myristoylated and palmitoylated serine/threonine-protein kinase, NTRK1_HUMAN, NUAK family SNF1-like kinase 2, NUAK2_HUMAN, Neurotrophic tyrosine kinase receptor type 1, Non-receptor tyrosine-protein kinase TNK1, OTTHUMP00000021377, OTTHUMP00000031340, OTTHUMP00000031341, OTTHUMP00000031342, OTTHUMP00000031343, OTTHUMP00000031344, OTTHUMP00000031345, OTTHUMP0000004234, OTTHUMP00000045860, OTTHUMP00000045861, OTTHUMP00000045862, OTTHUMP00000045863, OTTHUMP00000046113, OTTHUMP00000109090, OTTHUMP00000109091, OTTHUMP00000109094, OTTHUMP00000166071, OTTHUMP00000166072, OTTHUMP00000174799, OTTHUMP00000231338, OTTHUMP00000231339, Omphalocele kinase 2, Oncogene TRK, P21 protein (Cdc42/Rac) activated kinase 4, P34CDC2, P39 Mo15, PAK4_HUMAN, PAR1 homolog, PITALRE, PKB, PKL12, PPP1R47, PPP1R48, PPP1R71, PPP1R74, PSK2, PSSALRE, PTK, PTK1, PTK2 protein tyrosine kinase 2, PTK2B, PTK2B protein tyrosine kinase 2 beta, PYK2, Par 1a, Par 1b, Pe1Fe10, Pe1Fe13, Pe1Fe3, Pe1Fe6, Phosphoprotein NCP94, Pksc, Proline-rich tyrosine kinase 2, Prostate-derived sterile 20-like kinase 2, Protein kinase B, Protein kinase CDK5 splicing, Protein kinase Eg3, Protein kinase Krct, Protein kinase PK38, Protein kinase PKL12, Protein kinase STK10, Protein kinase expressed in day 12 fetal liver, Protein kinase minibrain homolog, Protein kinase related to S.cerevisiae STE20 effector for Cdc42Hs, Protein phosphatase 1 regulatory subunit 48, Protein phosphatase 1 regulatory subunit 71, Protein phosphatase 1 regulatory subunit 74, Protein phosphatase 1, regulatory subunit 47, Protein tyrosine kinase PTK1, Protein-tyrosine kinase 2, Protein-tyrosine kinase 2-beta, Proto oncogene tyrosine protein kinase FER, Proto-oncogene c-Fer, Ptk2, RAFTK, RAFTK2, RHOE, RP23 382O11.1, Receptor type tyrosine protein kinase FLT3, Related adhesion focal tyrosine kinase, SH3 domain containing proline rich kinase, SNARK, SNF1/AMP activated protein kinase, SNF1/AMP kinase-related kinase, SPDA1, SPRK, STE20-like kinase, STE20-like kinase MST1, STE20-like kinase MST2, STE20-like kinase PSK2, STK-1, STK12, STK15, STK16_HUMAN, STK3_HUMAN, STK4_HUMAN, STK5, STK6, STK6_HUMAN, STK7, Ser/Thr protein kinase PAR 1B, Ser/Thr protein kinase PAR-1, SerThr protein kinase PAR 1, Serine kinase, Serine threonine kinase PAK 4, Serine threonine kinase Stk1, Serine threonine protein kinase LATS1, Serine threonine protein kinase PSSALRE, Serine threonine protein kinase p78, Serine/theronine kinase 12, Serine/threonine kinase 15, Serine/threonine kinase 16, Serine/threonine kinase 3, Serine/threonine kinase 3 (STE20 homolog, yeast), Serine/threonine kinase 3 (Ste20, yeast homolog), Serine/threonine kinase 4, Serine/threonine kinase 6, Serine/threonine kinase 9, Serine/threonine kinase MNB, Serine/threonine kinase TAO1, Serine/threonine protein kinase 1, Serine/threonine protein kinase EMK, Serine/threonine protein kinase GSK3A, Serine/threonine protein kinase MO15, Serine/threonine protein kinase TAO1 homolog, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 16, Serine/threonine-protein kinase 3, Serine/threonine-protein kinase 4, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase 9, Serine/threonine-protein kinase GSK3B, Serine/threonine-protein kinase Krs-1, Serine/threonine-protein kinase Krs-2, Serine/threonine-protein kinase LATS1, Serine/threonine-protein kinase MARK2, Serine/threonine-protein kinase PAK 4, Serine/threonine-protein kinase PITALRE, Serine/threonine-protein kinase PSSALRE, Serine/threonine-protein kinase TAO1, Serine/threonine-protein kinase TAO3, Serine/threonine-protein kinase aurora-A, Serine/threonine-protein kinase aurora-B, Serine/threonine-protein kinase p78, Slow nerve growth, Src-homology 3 domain-containing proline-rich kinase, Stem cell tyrosine kinase 1, Stk9, TAK, TAO kinase 1, TAO kinase 3, TAOK1_HUMAN, TAOK3_HUMAN, TFIIH 80 kDa subunit, TFIIH Basal Transcription Factor Complex Helicase Subunit, TFIIH basal transcription factor complex 80 kDa subunit, TFIIH basal transcription factor complex helicase XPD subunit, TFIIH basal transcription factor complex kinase subunit, TFIIH basal transcription factor complex p80 subunit, TFIIH p80, TGF-beta-stimulated factor 1, TGFB stimulated factor 1, TIIAC, TNK1_HUMAN, TPKII catalytic subunit, TRK, TRK1, TRK1-transforming tyrosine kinase protein, TSF-1, TYK3, Tat associated kinase complex catalytic subunit, Tau protein kinase II catalytic subunit, Thousand and one amino acid protein 1, Thousand and one amino acid protein 3, Transforming growth factor beta stimulated factor 1, Trk-A, Tropomyosin-related kinase A, Tyrosine kinase 3, Tyrosine kinase non receptor 1, Tyrosine kinase receptor, Tyrosine kinase receptor A, Tyrosine protein kinase MELK, Tyrosine protein kinase STK16, Tyrosine-protein kinase Fer, Tyrosine-protein kinase receptor FLT3, WARTS, WARTS protein kinase, WEE 1 homolog 1 (S. pombe), WEE1 homolog (S. pombe), WEE1 homolog S. pombe, WEE1, S. pombe, homolog of, WEE1, somatic, WEE1A, WEE1_HUMAN, WEE1hu, WTS, Wee1 homolog, Wee1 tyrosine kinase, Wee1+ S. pombe homolog, Wee1+ homolog, Wee1-like protein kinase, Wee1A kinase, XPDC, Xeroderma pigmentosum complementary group D, Xeroderma pigmentosum group D-complementing protein, YSK3, arginine/serine-rich, c FER, cdc2-related protein kinase, cell division controller cholinesterase related, cell division cycle 2 like 5, cell division cycle 2 like 5 (cholinesterase related cell division controller), cyclin dependent kinase 2-alpha, cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase), gp140trk, h-warts, hARK1, hCDK12, hCDK13, hKFC-A, hKFC-B, hMELK, hMNB, hPSK, kiaa0904, kinase Cdc2, leukocyte antigen class I-B, mKIAA0175, mKIAA1361, major histocompatibility complex, class I, B, p125FAK, p14-TrkA, p140-TrkA, p21 Cdc42/Rac1-actiated kinase 4, p21(CDKN1A) activated kinase 4, p21-activated kinase 4, p33 protein kinase, p33(CDK2), p34 Cdk1, p34 protein kinase, p94-FER, pEg3 kinase, pp125FAK, wu:fc19e11, zgc:55383