DFFA
Function
Inhibitor of the caspase-activated DNase (DFF40).
Post-translational modifications
Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
Cellular localization
- Cytoplasm
Alternative names
DFF1, DFF45, H13, DFFA, DNA fragmentation factor subunit alpha, DNA fragmentation factor 45 kDa subunit, Inhibitor of CAD, DFF-45, ICAD