DGKK

Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:16210324, PubMed:23949095). Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable).

Lipid metabolism; glycerolipid metabolism.

Phosphorylated at Tyr-78 by some member of the SRC family in response to H(2)O(2).

Belongs to the eukaryotic diacylglycerol kinase family.

Expressed in testis, and to a lesser extent in placenta.

• Cell membrane
• Peripheral membrane protein

Diacylglycerol kinase kappa, DAG kinase kappa, DGK-kappa, 142 kDa diacylglycerol kinase, Diglyceride kinase kappa, DGKK

• entrezGene:139189
• swissprot:Q5KSL6

Proteins

Neuroscience

141829Da