DHX29
Function
ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
Sequence Similarities
Belongs to the DEAD box helicase family. DEAH subfamily.
Cellular localization
- Cytoplasm
Alternative names
DDX29, DHX29, ATP-dependent RNA helicase DHX29, DEAH box protein 29, Nucleic acid helicase DDXx