dinB
Function
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
Sequence Similarities
Belongs to the DNA polymerase type-Y family.
Cellular localization
- Cytoplasm
Alternative names
CPS_1040, dinB, DNA polymerase IV, Pol IV