Elevated levels of expression detected in the G2/M phase of synchronized cultures of HeLa cells.
Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Ubiquitinated, leading to its degradation.
Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells.
Belongs to the SAPAP family.
Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta.
DLG7, KIAA0008, DLGAP5, Disks large-associated protein 5, DAP-5, Discs large homolog 7, Disks large-associated protein DLG7, Hepatoma up-regulated protein, HURP
Proteins
Immuno-oncology
95115Da
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