DLK-1

May have a role in neuroendocrine differentiation.

N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.

Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue.

• Membrane
• Single-pass type I membrane protein
• Cytoplasm

DLK, DLK1, Protein delta homolog 1, DLK-1, pG2

• entrezGene:8788
• omim:176290
• swissprot:P80370

Proteins

Developmental Biology

41300Da