DLK1
Function
May have a role in neuroendocrine differentiation.
Post-translational modifications
N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.
Tissue Specificity
Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue.
Cellular localization
- Membrane
- Single-pass type I membrane protein
- Cytoplasm
Alternative names
DLK, DLK1, Protein delta homolog 1, DLK-1, pG2