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DNAI7

Function

Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function. May also act as a cell cycle regulator.

Post-translational modifications

Ubiquitinated. Ubiquitination leads to its degradation through the 26S proteasome. Ubiquitin-proteasome-mediated DNAI7 degradation occurs in mitosis.

Sequence Similarities

Belongs to the DNAI7 family.

Cellular localization

Alternative names

CASC1, CFAP94, LAS1, PPP1R54, DNAI7, Dynein axonemal intermediate chain 7, Cancer susceptibility candidate gene 1 protein, Cilia and flagella associated protein 94, Lung adenoma susceptibility 1-like protein, Protein phosphatase 1 regulatory subunit 54, Protein CASC1

swissprot:Q6TDU7 entrezGene:55259