DNER
Function
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).
Tissue Specificity
Expressed in brain, spinal cord and adrenal gland.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
- Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
Alternative names
BET, UNQ262/PRO299, DNER, Delta and Notch-like epidermal growth factor-related receptor