DPPA2
Function
Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes.
Tissue Specificity
Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues.
Cellular localization
- Nucleus
Alternative names
PESCRG1, DPPA2, Developmental pluripotency-associated protein 2, Pluripotent embryonic stem cell-related gene 1 protein