DPPA5
Developmental stage
Expressed in primordial germ (PGC), embryonic germ (EGC) and embryonic stem (ESC) cells. Not detected in embryonic carcinoma (ECC) cells.
Function
Involved in the maintenance of embryonic stem (ES) cell pluripotency. Dispensable for self-renewal of pluripotent ES cells and establishment of germ cells. Associates with specific target mRNAs (By similarity).
Sequence Similarities
Belongs to the KHDC1 family.
Cellular localization
- Cytoplasm
Alternative names
ESG1, DPPA5, Developmental pluripotency-associated 5 protein, hDPPA5, Embryonal stem cell-specific gene 1 protein, ESG-1