DRAM1
Function
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.
Sequence Similarities
Belongs to the DRAM/TMEM150 family.
Cellular localization
- Lysosome membrane
- Multi-pass membrane protein
Alternative names
DRAM, DRAM1, DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator