DUSP10
Function
Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38.
Sequence Similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Tissue Specificity
Expressed in keratinocytes (at protein level) (PubMed:29043977). Detected in brain (PubMed:16806267).
Cellular localization
- Cytoplasm
- Nucleus
Alternative names
MKP5, DUSP10, Dual specificity protein phosphatase 10, Mitogen-activated protein kinase phosphatase 5, MAP kinase phosphatase 5, MKP-5