Dual specificity protein phosphatase 21

Protein phosphatase component of the sperm flagellar doublet microtubules (By similarity). May act as a regulator of sperm motility by mediating dephosphorylation of sperm doublet microtubule proteins (By similarity). Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine (By similarity).

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Expressed in testis.

• Cytoplasm
• Nucleus
• Mitochondrion inner membrane
• Peripheral membrane protein
• Matrix side
• Cytoplasm
• Cytoskeleton
• Flagellum axoneme

LMWDSP21, DUSP21, Dual specificity protein phosphatase 21, Low molecular weight dual specificity phosphatase 21, LMW-DSP21

• entrezGene:63904
• omim:300678
• swissprot:Q9H596

Proteins

Oncology

21529Da