DUSP21
Function
Protein phosphatase component of the sperm flagellar doublet microtubules (By similarity). May act as a regulator of sperm motility by mediating dephosphorylation of sperm doublet microtubule proteins (By similarity). Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine (By similarity).
Sequence Similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Tissue Specificity
Expressed in testis.
Cellular localization
- Cytoplasm
- Nucleus
- Mitochondrion inner membrane
- Peripheral membrane protein
- Matrix side
- Cytoplasm
- Cytoskeleton
- Flagellum axoneme
Alternative names
LMWDSP21, DUSP21, Dual specificity protein phosphatase 21, Low molecular weight dual specificity phosphatase 21, LMW-DSP21