Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues.
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Abundant in brain, heart and skeletal muscle.
C11orf81, VH5, DUSP8, Dual specificity protein phosphatase 8, Dual specificity protein phosphatase hVH-5
Proteins
Oncology
65827Da
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