DYNC1LI2
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
Sequence Similarities
Belongs to the dynein light intermediate chain family.
Cellular localization
- Cytoplasm
- Cytoskeleton
Alternative names
DNCLI2, LIC2, DYNC1LI2, Cytoplasmic dynein 1 light intermediate chain 2, LIC53/55, LIC-2