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Function

Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and other enhanced proteolysis (PubMed:15496406). Promotes proteasome dissociation under oxidative stress (By similarity).

Sequence similarities

Belongs to the ECM29 family.

Cellular localization

  • Endoplasmic reticulum
  • Endoplasmic reticulum-Golgi intermediate compartment
  • Endosome
  • Cytoplasm
  • Cytoskeleton
  • Microtubule organizing center
  • Centrosome
  • Nucleus
  • Endosome
  • Multivesicular body
  • Cytoplasmic vesicle

Alternative names

ECM29, KIAA0368, ECPAS, Proteasome adapter and scaffold protein ECM29, Ecm29 proteasome adapter and scaffold, Proteasome-associated protein ECM29 homolog

Target type

Proteins

Molecular weight

204291Da

We found 1 product in 1 category

Primary Antibodies

Target

Application

Reactive species

Search our catalogue for 'ECPAS' (1)

Products